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Reproducible proteomics sample preparation for single FFPE tissue slices using acid-labile surfactant and direct trypsinization

BACKGROUND: Proteomic analyses of clinical specimens often rely on human tissues preserved through formalin-fixation and paraffin embedding (FFPE). Minimal sample consumption is the key to preserve the integrity of pathological archives but also to deal with minimal invasive core biopsies. This has...

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Detalles Bibliográficos
Autores principales: Föll, Melanie Christine, Fahrner, Matthias, Oria, Victor Oginga, Kühs, Markus, Biniossek, Martin Lothar, Werner, Martin, Bronsert, Peter, Schilling, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838928/
https://www.ncbi.nlm.nih.gov/pubmed/29527141
http://dx.doi.org/10.1186/s12014-018-9188-y

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