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Reproducible proteomics sample preparation for single FFPE tissue slices using acid-labile surfactant and direct trypsinization
BACKGROUND: Proteomic analyses of clinical specimens often rely on human tissues preserved through formalin-fixation and paraffin embedding (FFPE). Minimal sample consumption is the key to preserve the integrity of pathological archives but also to deal with minimal invasive core biopsies. This has...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838928/ https://www.ncbi.nlm.nih.gov/pubmed/29527141 http://dx.doi.org/10.1186/s12014-018-9188-y |