A missense mutation in MYH1 is associated with susceptibility to immune-mediated myositis in Quarter Horses

BACKGROUND: The cause of immune-mediated myositis (IMM), characterized by recurrent, rapid-onset muscle atrophy in Quarter Horses (QH), is unknown. The histopathologic hallmark of IMM is lymphocytic infiltration of myofibers. The purpose of this study was to identify putative functional variants ass...

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Detalles Bibliográficos
Autores principales: Finno, Carrie J., Gianino, Giuliana, Perumbakkam, Sudeep, Williams, Zoë J., Bordbari, Matthew H., Gardner, Keri L., Burns, Erin, Peng, Sichong, Durward-Akhurst, Sian A., Valberg, Stephanie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838957/
https://www.ncbi.nlm.nih.gov/pubmed/29510741
http://dx.doi.org/10.1186/s13395-018-0155-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838957/
https://www.ncbi.nlm.nih.gov/pubmed/29510741
http://dx.doi.org/10.1186/s13395-018-0155-0

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