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Petri net-based prediction of therapeutic targets that recover abnormally phosphorylated proteins in muscle atrophy

BACKGROUND: Muscle atrophy, an involuntary loss of muscle mass, is involved in various diseases and sometimes leads to mortality. However, therapeutics for muscle atrophy thus far have had limited effects. Here, we present a new approach for therapeutic target prediction using Petri net simulation o...

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Detalles Bibliográficos
Autores principales: Jung, Jinmyung, Kwon, Mijin, Bae, Sunghwa, Yim, Soorin, Lee, Doheon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838966/
https://www.ncbi.nlm.nih.gov/pubmed/29506508
http://dx.doi.org/10.1186/s12918-018-0555-0