Heme oxygenase-1 promoter region (GT)n polymorphism associates with increased neuroimmune activation and risk for encephalitis in HIV infection

BACKGROUND: Heme oxygenase-1 (HO-1) is a critical cytoprotective enzyme that limits oxidative stress, inflammation, and cellular injury within the central nervous system (CNS) and other tissues. We previously demonstrated that HO-1 protein expression is decreased within the brains of HIV+ subjects a...

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Detalles Bibliográficos
Autores principales: Gill, Alexander J., Garza, Rolando, Ambegaokar, Surendra S., Gelman, Benjamin B., Kolson, Dennis L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838989/
https://www.ncbi.nlm.nih.gov/pubmed/29510721
http://dx.doi.org/10.1186/s12974-018-1102-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838989/
https://www.ncbi.nlm.nih.gov/pubmed/29510721
http://dx.doi.org/10.1186/s12974-018-1102-z

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