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Targeted next generation sequencing identified clinically actionable mutations in patients with esophageal sarcomatoid carcinoma

BACKGROUND: Esophageal sarcomatoid carcinoma (ESC) is a rare disease with a mixture of both carcinomatous and sarcomatous components in the tumor. Its genetic background and mechanisms of oncogenesis remain largely unknown. METHODS: Here we performed targeted next generation sequencing (NGS) on a pa...

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Detalles Bibliográficos
Autores principales: Lu, Hongyang, Yang, Shifeng, Zhu, Huineng, Tong, Xiaoling, Xie, Fajun, Qin, Jing, Han, Na, Wu, Xue, Fan, Yun, Shao, Yang W., Mao, Weimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838991/
https://www.ncbi.nlm.nih.gov/pubmed/29506494
http://dx.doi.org/10.1186/s12885-018-4159-2