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Measuring multiple parameters of CD8+ tumor-infiltrating lymphocytes in human cancers by image analysis

BACKGROUND: Immuno-oncology and cancer immunotherapies are areas of intense research. The numbers and locations of CD8+ tumor-infiltrating lymphocytes (TILs) are important measures of the immune response to cancer with prognostic, pharmacodynamic, and predictive potential. We describe the developmen...

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Detalles Bibliográficos
Autores principales: Steele, Keith E., Tan, Tze Heng, Korn, René, Dacosta, Karma, Brown, Charles, Kuziora, Michael, Zimmermann, Johannes, Laffin, Brian, Widmaier, Moritz, Rognoni, Lorenz, Cardenes, Ruben, Schneider, Katrin, Boutrin, Anmarie, Martin, Philip, Zha, Jiping, Wiestler, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839005/
https://www.ncbi.nlm.nih.gov/pubmed/29510739
http://dx.doi.org/10.1186/s40425-018-0326-x