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Are doses of lamotrigine or levetiracetam adjusted during pregnancy?

Subtherapeutic levels of lamotrigine and levetiracetam are more likely to occur during pregnancy owing to the effect of pregnancy on their pharmacokinetics. This can lead to suboptimal control of epilepsy, and guidelines recommend proactive dose adjustment in the second and third trimesters alongsid...

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Detalles Bibliográficos
Autores principales: Richards, Noni, Reith, David, Stitely, Michael, Smith, Alesha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839303/
https://www.ncbi.nlm.nih.gov/pubmed/29588992
http://dx.doi.org/10.1002/epi4.12086