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CD44 exerts a functional role during EMT induction in cisplatin-resistant head and neck cancer cells

A number of studies report that epithelial to mesenchymal transition (EMT) supports the generation and maintenance of cancer stem cells (CSCs), which show tumor seeding ability and drug resistance; however, the molecular mechanisms underlying induction of EMT-associated tumor malignancy remain uncle...

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Detalles Bibliográficos
Autores principales: Miyazaki, Hiroaki, Takahashi, Ryou-u, Prieto-Vila, Marta, Kawamura, Yumi, Kondo, Seiji, Shirota, Tatsuo, Ochiya, Takahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839369/
https://www.ncbi.nlm.nih.gov/pubmed/29515788
http://dx.doi.org/10.18632/oncotarget.24252