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Overexpression of Cu-Zn SOD in Brucella abortus suppresses bacterial intracellular replication via down-regulation of Sar1 activity

Brucella Cu-Zn superoxide dismutase (Cu-Zn SOD) is a periplasmic protein, and immunization of mice with recombinant Cu-Zn SOD protein confers protection against Brucella abortus infection. However, the role of Cu-Zn SOD during the process of Brucella infection remains unknown. Here, we report that C...

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Detalles Bibliográficos
Autores principales: Liu, Xiaofeng, Zhou, Mi, Yang, Yanling, Wu, Jing, Peng, Qisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839387/
https://www.ncbi.nlm.nih.gov/pubmed/29515756
http://dx.doi.org/10.18632/oncotarget.24073