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Expression of TDRD9 in a subset of lung carcinomas by CpG island hypomethylation protects from DNA damage

Tudor domain containing protein 9 (TDRD9) is a RNA helicase normally expressed in the germline, where it is involved in the biosynthesis of PIWI-interacting RNAs (piRNAs). Here, we show that TDRD9 is highly expressed in a subset of non-small cell lung carcinomas and derived cell lines by hypomethyla...

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Detalles Bibliográficos
Autores principales: Guijo, Macarena, Ceballos-Chávez, María, Gómez-Marín, Elena, Basurto-Cayuela, Laura, Reyes, José C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839389/
https://www.ncbi.nlm.nih.gov/pubmed/29515758
http://dx.doi.org/10.18632/oncotarget.22709