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NFAT-mediated defects in erythropoiesis cause anemia in Il2(−/−) mice

The role of NFAT family transcription factors in erythropoiesis is so far unknown, although their involvement has been suggested previously. We have shown recently that Il2(-/-) mice develop severe anemia due to defects in KLF1 activity during BM erythropoiesis. Although, KLF1 activity is indispensa...

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Detalles Bibliográficos
Autores principales: Giampaolo, Sabrina, Wójcik, Gabriela, Klein-Hessling, Stefan, Serfling, Edgar, Patra, Amiya K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839390/
https://www.ncbi.nlm.nih.gov/pubmed/29515759
http://dx.doi.org/10.18632/oncotarget.23745