Unbiased compound-protein interface mapping and prediction of chemoresistance loci through forward genetics in haploid stem cells

Forward genetic screens in haploid mammalian cells have recently emerged as powerful tools for the discovery and investigation of recessive traits. Use of the haploid system provides unique genetic tractability and resolution. Upon positive selection, these screens typically employ analysis of loss-...

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Detalles Bibliográficos
Autores principales: Horn, Moritz, Kroef, Virginia, Allmeroth, Kira, Schuller, Nicole, Miethe, Stephan, Peifer, Martin, Penninger, Josef M., Elling, Ulrich, Denzel, Martin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839405/
https://www.ncbi.nlm.nih.gov/pubmed/29515774
http://dx.doi.org/10.18632/oncotarget.24305

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839405/
https://www.ncbi.nlm.nih.gov/pubmed/29515774
http://dx.doi.org/10.18632/oncotarget.24305

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