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RET mutation heterogeneity in primary advanced medullary thyroid cancers and their metastases

PURPOSE: Medullary Thyroid Cancer (MTC) whose pathogenesis is strictly related to RET proto-oncogene alterations, has been shown to have a heterogenic RET mutation profile in subpopulations of MTC. The aim of our study was to investigate the RET somatic mutation profile in primary MTC and in the cor...

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Detalles Bibliográficos
Autores principales: Romei, Cristina, Ciampi, Raffaele, Casella, Francesca, Tacito, Alessia, Torregrossa, Liborio, Ugolini, Clara, Basolo, Fulvio, Materazzi, Gabriele, Vitti, Paolo, Elisei, Rossella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839408/
https://www.ncbi.nlm.nih.gov/pubmed/29515777
http://dx.doi.org/10.18632/oncotarget.23986