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Bile acid metabolism regulated by the gut microbiota promotes non-alcoholic steatohepatitis-associated hepatocellular carcinoma in mice

Gut microbiota plays a significant role in the development of hepatocellular carcinoma (HCC) in non-alcoholic steatohepatitis (NASH). However, understanding of the precise mechanism of this process remains incomplete. A new class steatohepatitis-inducing high-fat diet (HFD), namely STHD-01, can prom...

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Detalles Bibliográficos
Autores principales: Yamada, Shoji, Takashina, Yoko, Watanabe, Mitsuhiro, Nagamine, Ryogo, Saito, Yoshimasa, Kamada, Nobuhiko, Saito, Hidetsugu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839411/
https://www.ncbi.nlm.nih.gov/pubmed/29515780
http://dx.doi.org/10.18632/oncotarget.24066