Urokinase-derived peptide UP-7 suppresses tumor angiogenesis and metastasis through inhibition of FAK activation

The recombinant kringle domain of urokinase (UK1) has been shown to inhibit angiogenesis and brain tumor growth in vivo. To avoid limitations in application due to mass production of recombinant protein, we attempted to develop a novel peptide inhibitor from UK1 sequence consisting of 83 amino acids...

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Detalles Bibliográficos
Autores principales: Kim, Hyun-Kyung, Naidansuren, Purevjargal, Lee, Seung Woo, Kim, Rae-Kwon, Lee, Su-Jae, Lee, Suk Keun, Hong, Yong-Kil, Joe, Young Ae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839413/
https://www.ncbi.nlm.nih.gov/pubmed/29515782
http://dx.doi.org/10.18632/oncotarget.24131

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839413/
https://www.ncbi.nlm.nih.gov/pubmed/29515782
http://dx.doi.org/10.18632/oncotarget.24131

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