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HMGA2 enhances 5-fluorouracil chemoresistance in colorectal cancer via the Dvl2/Wnt pathway

Drug resistance is one of the main hurdles to overcome for the improvement of cancer patient survival. However, the underlying mechanisms remain largely unknown, and therapeutic options are limited. Here, we demonstrate a strong correlation between HMGA2 expression and chemosensitivity to 5-fluorour...

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Detalles Bibliográficos
Autores principales: Xu, Xi, Wang, Yunfeng, Deng, Hong, Liu, Chungang, Wu, Jingjing, Lai, Maode
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839414/
https://www.ncbi.nlm.nih.gov/pubmed/29515783
http://dx.doi.org/10.18632/oncotarget.24133