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HMGA2 enhances 5-fluorouracil chemoresistance in colorectal cancer via the Dvl2/Wnt pathway
Drug resistance is one of the main hurdles to overcome for the improvement of cancer patient survival. However, the underlying mechanisms remain largely unknown, and therapeutic options are limited. Here, we demonstrate a strong correlation between HMGA2 expression and chemosensitivity to 5-fluorour...
Autores principales: | Xu, Xi, Wang, Yunfeng, Deng, Hong, Liu, Chungang, Wu, Jingjing, Lai, Maode |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839414/ https://www.ncbi.nlm.nih.gov/pubmed/29515783 http://dx.doi.org/10.18632/oncotarget.24133 |
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