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Effect of a Histone Deacetylases Inhibitor of IL-18 and TNF-Alpha Secretion in Vitro

BACKGROUND: Interleukin-18 (IL-18) and Tumor Necrosis Factor-alpha (TNF-α) are proinflammatory cytokines that increased the development of Th1 immune response, but have a different type of regulation of the gene expression. Whereas TNF-α has an inducible expression, IL-18 is translated as an inactiv...

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Detalles Bibliográficos
Autores principales: Dobreva, Zlatka Georgieva, Grigorov, Boncho Grigorov, Stanilova, Spaska Angelova
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Republic of Macedonia 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839430/
https://www.ncbi.nlm.nih.gov/pubmed/29531586
http://dx.doi.org/10.3889/oamjms.2018.075