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Recombinant Human Thioredoxin-1 Protects Macrophages from Oxidized Low-Density Lipoprotein-Induced Foam Cell Formation and Cell Apoptosis

Oxidized low-density lipoprotein (ox-LDL)-induced macrophage foam cell formation and apoptosis play critical roles in the pathogenesis of atherosclerosis. Thioredoxin-1 (Trx) is an antioxidant that potently protects various cells from oxidative stress-induced cell death. However, the protective effe...

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Detalles Bibliográficos
Autores principales: Zhang, Hui, Liu, Qi, Lin, Jia-Le, Wang, Yu, Zhang, Ruo-Xi, Hou, Jing-Bo, Yu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839490/
https://www.ncbi.nlm.nih.gov/pubmed/28554199
http://dx.doi.org/10.4062/biomolther.2016.275