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YH18968, a Novel 1,2,4-Triazolone G-Protein Coupled Receptor 119 Agonist for the Treatment of Type 2 Diabetes Mellitus

G protein-coupled receptor 119 (GPR119) is expressed in the pancreas and gastrointestinal tract, and its activation promotes insulin secretion in the beta cells of the pancreatic islets as well as the secretion of glucagon-like peptide-1 (GLP-1) in intestinal L cells, consequently improving glucose-...

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Detalles Bibliográficos
Autores principales: Han, Taedong, Lee, Byoung Moon, Park, Yoo Hoi, Lee, Dong Hoon, Choi, Hyun Ho, Lee, Taehoon, Kim, Hakwon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839499/
https://www.ncbi.nlm.nih.gov/pubmed/29495245
http://dx.doi.org/10.4062/biomolther.2018.011