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Immunodominance in T cell responses elicited against different domains of detoxified pneumolysin PlyD1
Detoxified pneumolysin, PlyD1, is a protein vaccine candidate that induces protection against infections with Streptococcus pneumoniae in mouse models. Despite extensive knowledge on antibody responses against PlyD1, limited information is available about PlyD1 induced T cell recognition. Here we in...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839544/ https://www.ncbi.nlm.nih.gov/pubmed/29509778 http://dx.doi.org/10.1371/journal.pone.0193650 |