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Immunodominance in T cell responses elicited against different domains of detoxified pneumolysin PlyD1

Detoxified pneumolysin, PlyD1, is a protein vaccine candidate that induces protection against infections with Streptococcus pneumoniae in mouse models. Despite extensive knowledge on antibody responses against PlyD1, limited information is available about PlyD1 induced T cell recognition. Here we in...

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Detalles Bibliográficos
Autores principales:	van Westen, Els, Poelen, Martien C. M., van den Dobbelsteen, Germie P. J. M., Oloo, Eliud O., Ochs, Martina M., Rots, Nynke Y., van Els, Cecile A. C. M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839544/ https://www.ncbi.nlm.nih.gov/pubmed/29509778 http://dx.doi.org/10.1371/journal.pone.0193650

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