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CENP-C/H/I/K/M/T/W/N/L and hMis12 but not CENP-S/X participate in complex formation in the nucleoplasm of living human interphase cells outside centromeres

Kinetochore proteins assemble onto centromeric chromatin and regulate DNA segregation during cell division. The inner kinetochore proteins bind centromeres while most outer kinetochore proteins assemble at centromeres during mitosis, connecting the complex to microtubules. Here, we measured the co-m...

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Detalles Bibliográficos
Autores principales: Hoischen, Christian, Yavas, Sibel, Wohland, Thorsten, Diekmann, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839545/
https://www.ncbi.nlm.nih.gov/pubmed/29509805
http://dx.doi.org/10.1371/journal.pone.0192572