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The dynamic shuttling of SIRT1 between cytoplasm and nuclei in bronchial epithelial cells by single and repeated cigarette smoke exposure

SIRT1 (silent information regulator 2 homolog 1) is a crucial cellular survival protein especially in oxidative stress environments, and has been thought to locate within the nuclei, but also known to shuttle between cytoplasm and nuclei in some cell types. Here, we show for the first time the dynam...

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Detalles Bibliográficos
Autores principales: Yanagisawa, Satoru, Baker, Jonathan R., Vuppusetty, Chaitanya, Koga, Takeshi, Colley, Thomas, Fenwick, Peter, Donnelly, Louise E., Barnes, Peter J., Ito, Kazuhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839577/
https://www.ncbi.nlm.nih.gov/pubmed/29509781
http://dx.doi.org/10.1371/journal.pone.0193921