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MicroRNA-223 Suppresses the Canonical NF-κB Pathway in Basal Keratinocytes to Dampen Neutrophilic Inflammation

MicroRNA-223 is known as a myeloid-enriched anti-inflammatory microRNA that is dysregulated in numerous inflammatory conditions. Here, we report that neutrophilic inflammation (wound response) is augmented in miR-223-deficient zebrafish, due primarily to elevated activation of the canonical nuclear...

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Detalles Bibliográficos
Autores principales: Zhou, Wenqing, Pal, Arpita S., Hsu, Alan Yi-Hui, Gurol, Theodore, Zhu, Xiaoguang, Wirbisky-Hershberger, Sara E., Freeman, Jennifer L., Kasinski, Andrea L., Deng, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839657/
https://www.ncbi.nlm.nih.gov/pubmed/29444433
http://dx.doi.org/10.1016/j.celrep.2018.01.058