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MicroRNA-223 Suppresses the Canonical NF-κB Pathway in Basal Keratinocytes to Dampen Neutrophilic Inflammation
MicroRNA-223 is known as a myeloid-enriched anti-inflammatory microRNA that is dysregulated in numerous inflammatory conditions. Here, we report that neutrophilic inflammation (wound response) is augmented in miR-223-deficient zebrafish, due primarily to elevated activation of the canonical nuclear...
Autores principales: | Zhou, Wenqing, Pal, Arpita S., Hsu, Alan Yi-Hui, Gurol, Theodore, Zhu, Xiaoguang, Wirbisky-Hershberger, Sara E., Freeman, Jennifer L., Kasinski, Andrea L., Deng, Qing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839657/ https://www.ncbi.nlm.nih.gov/pubmed/29444433 http://dx.doi.org/10.1016/j.celrep.2018.01.058 |
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