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Protein phosphorylation maintains the normal function of cloned human Ca(v)2.3 channels

R-type currents mediated by native and recombinant Ca(v)2.3 voltage-gated Ca(2+) channels (VGCCs) exhibit facilitation (run-up) and subsequent decline (run-down) in whole-cell patch-clamp recordings. A better understanding of the two processes could provide insight into constitutive modulation of th...

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Detalles Bibliográficos
Autores principales: Neumaier, Felix, Alpdogan, Serdar, Hescheler, Jürgen, Schneider, Toni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839719/
https://www.ncbi.nlm.nih.gov/pubmed/29453293
http://dx.doi.org/10.1085/jgp.201711880