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Stac3 enhances expression of human Ca(V)1.1 in Xenopus oocytes and reveals gating pore currents in HypoPP mutant channels
Mutations of Ca(V)1.1, the pore-forming subunit of the L-type Ca(2+) channel in skeletal muscle, are an established cause of hypokalemic periodic paralysis (HypoPP). However, functional assessment of HypoPP mutant channels has been hampered by difficulties in achieving sufficient plasma membrane exp...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Rockefeller University Press
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839724/ https://www.ncbi.nlm.nih.gov/pubmed/29386226 http://dx.doi.org/10.1085/jgp.201711962 |