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GPR56/ADGRG1 regulates development and maintenance of peripheral myelin

Myelin is a multilamellar sheath generated by specialized glia called Schwann cells (SCs) in the peripheral nervous system (PNS), which serves to protect and insulate axons for rapid neuronal signaling. In zebrafish and rodent models, we identify GPR56/ADGRG1 as a conserved regulator of PNS developm...

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Detalles Bibliográficos
Autores principales: Ackerman, Sarah D., Luo, Rong, Poitelon, Yannick, Mogha, Amit, Harty, Breanne L., D’Rozario, Mitchell, Sanchez, Nicholas E., Lakkaraju, Asvin K.K., Gamble, Paul, Li, Jun, Qu, Jun, MacEwan, Matthew R., Ray, Wilson Zachary, Aguzzi, Adriano, Feltri, M. Laura, Piao, Xianhua, Monk, Kelly R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839751/
https://www.ncbi.nlm.nih.gov/pubmed/29367382
http://dx.doi.org/10.1084/jem.20161714