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Deficiency in T follicular regulatory cells promotes autoimmunity

T follicular regulatory (Tfr) cells are a new subset of regulatory T (T reg) cells localized in the germinal center to limit the humoral response. Until now, the physiological function of Tfr cells has been largely unknown. In this study, we developed a Bcl6(fl/fl)Foxp3Cre mouse to analyze the funct...

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Detalles Bibliográficos
Autores principales: Fu, Weiwei, Liu, Xindong, Lin, Xiang, Feng, Han, Sun, Lin, Li, Shuran, Chen, Hairong, Tang, Hong, Lu, Liwei, Jin, Wei, Dong, Chen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839755/
https://www.ncbi.nlm.nih.gov/pubmed/29378778
http://dx.doi.org/10.1084/jem.20170901