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Sustained Id2 regulation of E proteins is required for terminal differentiation of effector CD8(+) T cells

CD8(+) T cells responding to infection differentiate into a heterogeneous population composed of progeny that are short-lived and participate in the immediate, acute response and those that provide long-lasting host protection. Although it is appreciated that distinct functional and phenotypic CD8(+...

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Detalles Bibliográficos
Autores principales: Omilusik, Kyla D., Nadjsombati, Marija S., Shaw, Laura A., Yu, Bingfei, Milner, J. Justin, Goldrath, Ananda W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839762/
https://www.ncbi.nlm.nih.gov/pubmed/29440362
http://dx.doi.org/10.1084/jem.20171584