The Cullin-3–Rbx1–KCTD10 complex controls endothelial barrier function via K63 ubiquitination of RhoB

RhoGTPases control endothelial cell (EC) migration, adhesion, and barrier formation. Whereas the relevance of RhoA for endothelial barrier function is widely accepted, the role of the RhoA homologue RhoB is poorly defined. RhoB and RhoA are 85% identical, but RhoB’s subcellular localization and half...

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Detalles Bibliográficos
Autores principales: Kovačević, Igor, Sakaue, Tomohisa, Majoleé, Jisca, Pronk, Manon C., Maekawa, Masashi, Geerts, Dirk, Fernandez-Borja, Mar, Higashiyama, Shigeki, Hordijk, Peter L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839774/
https://www.ncbi.nlm.nih.gov/pubmed/29358211
http://dx.doi.org/10.1083/jcb.201606055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839774/
https://www.ncbi.nlm.nih.gov/pubmed/29358211
http://dx.doi.org/10.1083/jcb.201606055

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