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Rab18 promotes lipid droplet (LD) growth by tethering the ER to LDs through SNARE and NRZ interactions

Lipid incorporation from endoplasmic reticulum (ER) to lipid droplet (LD) is important in controlling LD growth and intracellular lipid homeostasis. However, the molecular link mediating ER and LD cross talk remains elusive. Here, we identified Rab18 as an important Rab guanosine triphosphatase in c...

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Detalles Bibliográficos
Autores principales: Xu, Dijin, Li, Yuqi, Wu, Lizhen, Li, Ying, Zhao, Dongyu, Yu, Jinhai, Huang, Tuozhi, Ferguson, Charles, Parton, Robert G., Yang, Hongyuan, Li, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839781/
https://www.ncbi.nlm.nih.gov/pubmed/29367353
http://dx.doi.org/10.1083/jcb.201704184