Src- and confinement-dependent FAK activation causes E-cadherin relaxation and β-catenin activity

In epithelia, E-cadherin cytoplasmic tail is under cytoskeleton-generated tension via a link that contains β-catenin. A cotranscription factor, β-catenin, is also active in morphogenetic processes associated with epithelial-to-mesenchymal transition. β-Catenin signaling appears mechanically inducibl...

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Detalles Bibliográficos
Autores principales: Gayrard, Charlène, Bernaudin, Clément, Déjardin, Théophile, Seiler, Cynthia, Borghi, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839785/
https://www.ncbi.nlm.nih.gov/pubmed/29311227
http://dx.doi.org/10.1083/jcb.201706013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839785/
https://www.ncbi.nlm.nih.gov/pubmed/29311227
http://dx.doi.org/10.1083/jcb.201706013

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