Enucleated cells reveal differential roles of the nucleus in cell migration, polarity, and mechanotransduction

The nucleus has long been postulated to play a critical physical role during cell polarization and migration, but that role has not been defined or rigorously tested. Here, we enucleated cells to test the physical necessity of the nucleus during cell polarization and directed migration. Using enucle...

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Detalles Bibliográficos
Autores principales: Graham, David M., Andersen, Tomas, Sharek, Lisa, Uzer, Gunes, Rothenberg, Katheryn, Hoffman, Brenton D., Rubin, Janet, Balland, Martial, Bear, James E., Burridge, Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839789/
https://www.ncbi.nlm.nih.gov/pubmed/29351995
http://dx.doi.org/10.1083/jcb.201706097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839789/
https://www.ncbi.nlm.nih.gov/pubmed/29351995
http://dx.doi.org/10.1083/jcb.201706097

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