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Enucleated cells reveal differential roles of the nucleus in cell migration, polarity, and mechanotransduction
The nucleus has long been postulated to play a critical physical role during cell polarization and migration, but that role has not been defined or rigorously tested. Here, we enucleated cells to test the physical necessity of the nucleus during cell polarization and directed migration. Using enucle...
Autores principales: | Graham, David M., Andersen, Tomas, Sharek, Lisa, Uzer, Gunes, Rothenberg, Katheryn, Hoffman, Brenton D., Rubin, Janet, Balland, Martial, Bear, James E., Burridge, Keith |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839789/ https://www.ncbi.nlm.nih.gov/pubmed/29351995 http://dx.doi.org/10.1083/jcb.201706097 |
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