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Protease signaling regulates apical cell extrusion, cell contacts, and proliferation in epithelia

Mechanisms that sense and regulate epithelial morphogenesis, integrity, and homeostasis are incompletely understood. Protease-activated receptor 2 (Par2), the Par2-activating membrane-tethered protease matriptase, and its inhibitor, hepatocyte activator inhibitor 1 (Hai1), are coexpressed in most ep...

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Detalles Bibliográficos
Autores principales: Schepis, Antonino, Barker, Adrian, Srinivasan, Yoga, Balouch, Eaman, Zheng, Yaowu, Lam, Ian, Clay, Hilary, Hsiao, Chung-Der, Coughlin, Shaun R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839797/
https://www.ncbi.nlm.nih.gov/pubmed/29301867
http://dx.doi.org/10.1083/jcb.201709118