Improving Assessment of Drug Safety Through Proteomics: Early Detection and Mechanistic Characterization of the Unforeseen Harmful Effects of Torcetrapib

BACKGROUND: Early detection of adverse effects of novel therapies and understanding of their mechanisms could improve the safety and efficiency of drug development. We have retrospectively applied large-scale proteomics to blood samples from ILLUMINATE (Investigation of Lipid Level Management to Und...

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Detalles Bibliográficos
Autores principales: Williams, Stephen A., Murthy, Ashwin C., DeLisle, Robert K., Hyde, Craig, Malarstig, Anders, Ostroff, Rachel, Weiss, Sophie J., Segal, Mark R., Ganz, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839936/
https://www.ncbi.nlm.nih.gov/pubmed/28974520
http://dx.doi.org/10.1161/CIRCULATIONAHA.117.028213

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839936/
https://www.ncbi.nlm.nih.gov/pubmed/28974520
http://dx.doi.org/10.1161/CIRCULATIONAHA.117.028213

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