Telomerase Reverse Transcriptase Promoter Alterations Across Cancer Types as Detected by Next-Generation Sequencing: A Clinical and Molecular Analysis of 423 Patients

BACKGROUND: Telomerase reverse transcriptase (TERT) promoter mutations that may affect telomerase activity have recently been described in human malignancies. The purpose of this study was to investigate the clinical correlates of TERT promoter abnormalities in a large cohort of patients with divers...

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Detalles Bibliográficos
Autores principales: Schwaederle, Maria, Krishnamurthy, Nithya, Daniels, Gregory A., Piccioni, David E., Kesari, Santosh, Fanta, Paul T., Schwab, Richard B., Patel, Sandip P., Parker, Barbara A., Kurzrock, Razelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839978/
https://www.ncbi.nlm.nih.gov/pubmed/29211306
http://dx.doi.org/10.1002/cncr.31175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839978/
https://www.ncbi.nlm.nih.gov/pubmed/29211306
http://dx.doi.org/10.1002/cncr.31175

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