Yeast surface display platform for rapid discovery of conformationally selective nanobodies

Camelid single-domain antibody fragments (“nanobodies”) provide the remarkable specificity of antibodies within a single 15 kDa immunoglobulin V(HH) domain. This unique feature has enabled applications ranging from use as biochemical tools to therapeutic agents. Nanobodies have emerged as especially...

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Detalles Bibliográficos
Autores principales: McMahon, Conor, Baier, Alexander S., Pascolutti, Roberta, Wegrecki, Marcin, Zheng, Sanduo, Ong, Janice X., Erlandson, Sarah C., Hilger, Daniel, Rasmussen, Søren G. F., Ring, Aaron M., Manglik, Aashish, Kruse, Andrew C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839991/
https://www.ncbi.nlm.nih.gov/pubmed/29434346
http://dx.doi.org/10.1038/s41594-018-0028-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5839991/
https://www.ncbi.nlm.nih.gov/pubmed/29434346
http://dx.doi.org/10.1038/s41594-018-0028-6

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