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Screening, large-scale production, and structure-based classification for cystine-dense peptides

Peptides folded through interwoven disulfides display extreme biochemical properties and unique medicinal potential. Their exploitation was hampered by the limited amounts isolatable from natural sources and the expense of chemical synthesis. We developed reliable biological methods for high-through...

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Detalles Bibliográficos
Autores principales: Correnti, Colin E., Gewe, Mesfin M., Mehlin, Christopher, Bandaranayake, Ashok D., Johnsen, William A., Rupert, Peter B., Brusniak, Mi-Youn, Clarke, Midori, Burke, Skyler E., de van der Schueren, Willem, Pilat, Kristina, Turnbaugh, Shanon M., May, Damon, Watson, Alex, Chan, Man Kid, Bahl, Christopher D., Olson, James M., Strong, Roland K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840021/
https://www.ncbi.nlm.nih.gov/pubmed/29483648
http://dx.doi.org/10.1038/s41594-018-0033-9