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Screening, large-scale production, and structure-based classification for cystine-dense peptides
Peptides folded through interwoven disulfides display extreme biochemical properties and unique medicinal potential. Their exploitation was hampered by the limited amounts isolatable from natural sources and the expense of chemical synthesis. We developed reliable biological methods for high-through...
Autores principales: | Correnti, Colin E., Gewe, Mesfin M., Mehlin, Christopher, Bandaranayake, Ashok D., Johnsen, William A., Rupert, Peter B., Brusniak, Mi-Youn, Clarke, Midori, Burke, Skyler E., de van der Schueren, Willem, Pilat, Kristina, Turnbaugh, Shanon M., May, Damon, Watson, Alex, Chan, Man Kid, Bahl, Christopher D., Olson, James M., Strong, Roland K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840021/ https://www.ncbi.nlm.nih.gov/pubmed/29483648 http://dx.doi.org/10.1038/s41594-018-0033-9 |
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