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Tumor necrosis factor α-converting enzyme inhibitor attenuates lipopolysaccharide-induced reactive oxygen species and mitogen-activated protein kinase expression in human renal proximal tubule epithelial cells

Tumor necrosis factor-α (TNFα) and the angiotensin system are involved in inflammatory diseases and may contribute to acute kidney injury. We investigated the mechanisms by which TNFα-converting enzyme (TACE) contributes to lipopolysaccharide (LPS)-induced renal inflammation and the effect of TACE i...

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Detalles Bibliográficos
Autores principales: Bae, Eun Hui, Kim, In Jin, Choi, Hong Sang, Kim, Ha Yeon, Kim, Chang Seong, Ma, Seong Kwon, Kim, In S., Kim, Soo Wan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840072/
https://www.ncbi.nlm.nih.gov/pubmed/29520166
http://dx.doi.org/10.4196/kjpp.2018.22.2.135