Fluvastatin inhibits advanced glycation end products-induced proliferation, migration, and extracellular matrix accumulation in vascular smooth muscle cells by targeting connective tissue growth factor

Connective tissue growth factor (CTGF) is a novel fibrotic mediator, which is considered to mediate fibrosis through extracellular matrix (ECM) synthesis in diabetic cardiovascular complications. Statins have significant immunomodulatory effects and reduce vascular injury. We therefore examined whet...

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Detalles Bibliográficos
Autores principales: Hwang, Ae-Rang, Nam, Ju-Ock, Kang, Young Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2018
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840078/
https://www.ncbi.nlm.nih.gov/pubmed/29520172
http://dx.doi.org/10.4196/kjpp.2018.22.2.193

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840078/
https://www.ncbi.nlm.nih.gov/pubmed/29520172
http://dx.doi.org/10.4196/kjpp.2018.22.2.193

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