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Caloric Restriction Mimetic 2-Deoxyglucose Alleviated Inflammatory Lung Injury via Suppressing Nuclear Pyruvate Kinase M2–Signal Transducer and Activator of Transcription 3 Pathway

Inflammation is an energy-intensive process, and caloric restriction (CR) could provide anti-inflammatory benefits. CR mimetics (CRM), such as the glycolytic inhibitor 2-deoxyglucose (2-DG), mimic the beneficial effects of CR without inducing CR-related physiologic disturbance. This study investigat...

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Detalles Bibliográficos
Autores principales: Hu, Kai, Yang, Yongqiang, Lin, Ling, Ai, Qing, Dai, Jie, Fan, Kerui, Ge, Pu, Jiang, Rong, Wan, Jingyuan, Zhang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840172/
https://www.ncbi.nlm.nih.gov/pubmed/29552018
http://dx.doi.org/10.3389/fimmu.2018.00426