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In Utero Exposure to Exosomal and B-Cell Alloantigens Lessens Alloreactivity of Recipients’ Lymphocytes Rather than Confers Allograft Tolerance

According to actively acquired tolerance, antigen exposure before full immune development in fetal or early neonatal life will cause tolerance to this specific antigen. In this study, we aimed to examine whether allogeneic tolerance could be elicited by in utero exposure to surface MHC antigens of a...

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Detalles Bibliográficos
Autores principales: Chen, Jeng-Chang, Ou, Liang-Shiou, Chan, Cheng-Chi, Kuo, Ming-Ling, Tseng, Li-Yun, Chang, Hsueh-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840197/
https://www.ncbi.nlm.nih.gov/pubmed/29552016
http://dx.doi.org/10.3389/fimmu.2018.00418