Autoantibodies May Predict Immune-Related Toxicity: Results from a Phase I Study of Intralesional Bacillus Calmette–Guérin followed by Ipilimumab in Patients with Advanced Metastatic Melanoma

Immune checkpoint inhibitors (ICIs) have revolutionized the treatment of advanced melanoma. The first ICI to demonstrate clinical benefit, ipilimumab, targets cytotoxic T-lymphocyte-associated antigen-4 (CTLA-4); however, the long-term overall survival is just 22%. More than 40 years ago intralesion...

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Detalles Bibliográficos
Autores principales: Da Gama Duarte, Jessica, Parakh, Sagun, Andrews, Miles C., Woods, Katherine, Pasam, Anupama, Tutuka, Candani, Ostrouska, Simone, Blackburn, Jonathan M., Behren, Andreas, Cebon, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840202/
https://www.ncbi.nlm.nih.gov/pubmed/29552014
http://dx.doi.org/10.3389/fimmu.2018.00411

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840202/
https://www.ncbi.nlm.nih.gov/pubmed/29552014
http://dx.doi.org/10.3389/fimmu.2018.00411

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