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Combination of Ipilimumab and Adoptive Cell Therapy with Tumor-Infiltrating Lymphocytes for Patients with Metastatic Melanoma

PURPOSE: Adoptive cell therapy (ACT) using tumor-infiltrating lymphocytes (TIL) for metastatic melanoma can be highly effective, but attrition due to progression before TIL administration (32% in prior institutional experience) remains a limitation. We hypothesized that combining ACT with cytotoxic...

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Detalles Bibliográficos
Autores principales: Mullinax, John E., Hall, MacLean, Prabhakaran, Sangeetha, Weber, Jeffrey, Khushalani, Nikhil, Eroglu, Zeynep, Brohl, Andrew S., Markowitz, Joseph, Royster, Erica, Richards, Allison, Stark, Valerie, Zager, Jonathan S., Kelley, Linda, Cox, Cheryl, Sondak, Vernon K., Mulé, James J., Pilon-Thomas, Shari, Sarnaik, Amod A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840208/
https://www.ncbi.nlm.nih.gov/pubmed/29552542
http://dx.doi.org/10.3389/fonc.2018.00044