Insights into the ubiquitin-proteasome system of human embryonic stem cells

Human embryonic stem cells (hESCs) exhibit high levels of proteasome activity, an intrinsic characteristic required for their self-renewal, pluripotency and differentiation. However, the mechanisms by which enhanced proteasome activity maintains hESC identity are only partially understood. Besides i...

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Detalles Bibliográficos
Autores principales: Saez, Isabel, Koyuncu, Seda, Gutierrez-Garcia, Ricardo, Dieterich, Christoph, Vilchez, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840266/
https://www.ncbi.nlm.nih.gov/pubmed/29511261
http://dx.doi.org/10.1038/s41598-018-22384-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840266/
https://www.ncbi.nlm.nih.gov/pubmed/29511261
http://dx.doi.org/10.1038/s41598-018-22384-9

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