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Insights into the ubiquitin-proteasome system of human embryonic stem cells
Human embryonic stem cells (hESCs) exhibit high levels of proteasome activity, an intrinsic characteristic required for their self-renewal, pluripotency and differentiation. However, the mechanisms by which enhanced proteasome activity maintains hESC identity are only partially understood. Besides i...
Autores principales: | Saez, Isabel, Koyuncu, Seda, Gutierrez-Garcia, Ricardo, Dieterich, Christoph, Vilchez, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5840266/ https://www.ncbi.nlm.nih.gov/pubmed/29511261 http://dx.doi.org/10.1038/s41598-018-22384-9 |
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